I am so sorry this runs in your family Ellen and for the losses you have dealt with, it's terribly unfair. I relate to this on a couple of levels. Having had lymphoma young, I don't know if I would want to know. I definitely didn't opt to know any more medical issues with 23 and Me. I can understand why you have chosen not to know so far. I have a higher risk of breast cancer because of my other cancer treatment ironically and I hate the feeling of it looming over me. I am so glad your sister doesn't have the gene/markers. I don't know if mine had any genetic basis because my dad was adopted. On the diet/lifestyle front, I am fairly sceptical. I was a vegetarian for ten years and did a very clean detox diet in the months before I first had symptoms, so my faith in that stuff pretty much went out the window. I think aside from smoking and weight there is not much we can do unfortunately. Obviously no harm in it but like you say it has to come from a place of really wanting to do it. It is fascinating to me that science is giving people this information, I wonder how many people sign up for it. The psychological effects of a potential disease threat may impact people's lives for the worse in the long run, it's so tricky.